Anti-COX-2 (mouse) (aa 584-598)

Anti-COX-2 (mouse) (aa 584-598)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay160126-1 1 each -

6 - 10 business days*

422.00€
 
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase... more
Product information "Anti-COX-2 (mouse) (aa 584-598)"
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2, Cay-17010), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2 (Cay-17020). COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosynthesis of PGs under acute inflammatory conditions. Thus, COX-2 has been the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development. Cayman's COX-2 (mouse) Polyclonal Antibody (aa 584-598) can be used for immunofluorescence (IF), immunohistochemistry (IHC), and Western blot (WB) applications. The antibody recognizes a unique C-terminal region of COX-2 that is not present in COX-1, specifically detecting COX-2 at 72 kDa from human, macaque monkey, mouse, ovine, and rat samples.Synonyms: Cyclooxygenase 2, PGHS-2, Prostaglandin H Synthase 2. Immunogen: Synthetic peptide corresponding to the C-terminal region of mouse COX-2. MW: 72 kDa. Formulation: (Request formulation change), Peptide affinity-purified polyclonal antibody. Storage Buffer: PBS, pH 7.2 with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Isotype: IgG. Applications: IF, IHC, WB. Cross Reactivity: (+) COX-2, (-) COX-1 (all species). UniProt Accession #: Q05769. Origin: Animal/Rabbit.
Keywords: Anti-Cox-2, Anti-COX-2, Anti-PES-2, Anti-COX-2, Anti-PES-2, Anti-PHS II, Anti-PGHS-2, Anti-PHS II, Anti-PGHS-2, Anti-Gripghs, Anti-Gripghs, Anti-TIS10 protein, Anti-TIS10 protein, Anti-PGH synthase 2, Anti-PGH synthase 2, Anti-Cyclooxygenase-2, Anti-Cyclo
Supplier: Cayman Chemical
Supplier-Nr: 160126

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: murine, rat, human, ovine (Expected: bovine, canine)
Immunogen: Synthetic peptide from the C-terminal region of mouse COX-2
Format: Solid

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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