Anti-COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2)

Anti-COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C7904-80F.100 100 µg - -

3 - 19 business days*

1,007.00€
 
Cyclooxygenase-2 (COX2) also known as prostaglandin G/H synthase 2 (PGHS2) is a 70kD microsomal... more
Product information "Anti-COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2)"
Cyclooxygenase-2 (COX2) also known as prostaglandin G/H synthase 2 (PGHS2) is a 70kD microsomal enzyme that belongs to the prostaglandin G/H synthase family. It is inducibly-expressed by a number of cell types, including fibroblasts, vascular smooth muscle cells, endothelium, and monocytes. Functionally, COX2 is a homodimer that catalyzes two steps in the conversion of arachadonic acid to prostaglandin H 2. Mature human COX2 is 587 amino acids (aa) in length and contains one EGF-like domain (aa 18-55), a potential membrane interacting region (aa 277-292) and a globular catalytic domain (aa 293-604). At least one splice form exists that shows an 11 aa substitution for the C-terminal 451 amino acids. Mature human COX2 shows 87% aa identity to mouse COX2. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: C7904-80F

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: human, mouse
Immunogen: E. coli-derived recombinant human Cyclooxygenase 2 (aa18-604) SwissProt # P35354
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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