Anti-CNGA3

Anti-CNGA3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-65434.60 60 µl -

7 - 16 business days*

198.00€
E-AB-65434.120 120 µl -

7 - 16 business days*

317.00€
E-AB-65434.200 200 µl -

7 - 16 business days*

525.00€
 
This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is... more
Product information "Anti-CNGA3"
This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different isoforms have been described. Protein function: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3. Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones. [The UniProt Consortium]
Keywords: Anti-CNG3, Anti-CNG-3, Anti-CNGA3, Anti-CNCG3, Anti-CNG channel alpha-3, Anti-Cyclic nucleotide-gated channel alpha-3, Anti-Cyclic nucleotide-gated cation channel alpha-3, Anti-Cone photoreceptor cGMP-gated channel subunit alpha, CNGA3 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-65434

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human CNGA3

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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