Anti-Chk 1 (Checkpoint Kinase 1, CHEK1, CHK1, Serine/threonine-protein Kinase Chk1)

Anti-Chk 1 (Checkpoint Kinase 1, CHEK1, CHK1, Serine/threonine-protein Kinase Chk1)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030095.100 100 µl - -

3 - 19 business days*

410.00€
 
CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in... more
Product information "Anti-Chk 1 (Checkpoint Kinase 1, CHEK1, CHK1, Serine/threonine-protein Kinase Chk1)"
CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Chk1 can also phosphorylate p53 at Ser20 in vitro. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-CHK1, Anti-CHEK1, EC=2.7.11.1, Anti-Checkpoint kinase-1, Anti-CHK1 checkpoint homolog, Anti-Cell cycle checkpoint kinase, Anti-Serine/threonine-protein kinase Chk1
Supplier: United States Biological
Supplier-Nr: 030095

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B173
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse
Immunogen: Purified recombinant fragment of CHK1 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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