Anti-Cdx2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-35-1812-50	50 µl		-		3 - 11 business days*		574.00€

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Involved in the transcriptional regulation of multiple genes expressed in the intestinal... more

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Product information "Anti-Cdx2"

Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Inamori K., Takeshita K., Chiba S., Yazaki Y., Hirai H.Biochem. Biophys. Res. Commun. 196:203-208(1993) Protein function: Transcription factor which regulates the transcription of multiple genes expressed in the intestinal epithelium. Binds to the promoter of the intestinal sucrase-isomaltase SI and activates SI transcription. Binds to the DNA sequence 5'-ATAAAAACTTAT-3' in the promoter region of VDR and activates VDR transcription. Binds to and activates transcription of LPH. Activates transcription of CLDN2 and intestinal mucin MUC2. Binds to the 5'-AATTTTTTACAACACCT-3' DNA sequence in the promoter region of CA1 and activates CA1 transcription. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA (PubMed:28473536). [The UniProt Consortium]

Keywords:	Anti-CDX3, Anti-CDX2, Anti-CDX-3, Anti-Homeobox protein CDX-2, Anti-Caudal-type homeobox protein 2, Polyclonal Antibody to Cdx2
Supplier:	Abeomics
Supplier-Nr:	35-1812-50

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat, mk
Immunogen:	Peptide sequence around aa.12~16(S-M-Y-P-S) derived from Human Cdx2
Format:	Purified