Anti-CDK5 (Cyclin-Dependent Kinase 5, Cell Division Protein Kinase 5, Cyclin-dependent Kinase 5, Ser

Anti-CDK5 (Cyclin-Dependent Kinase 5, Cell Division Protein Kinase 5, Cyclin-dependent Kinase 5, Ser
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2575-10B.100 100 µl - -

3 - 19 business days*

476.00€
 
Cyclin-dependent kinase-5(CDK5) is a member of the cyclin-dependent kinase family of... more
Product information "Anti-CDK5 (Cyclin-Dependent Kinase 5, Cell Division Protein Kinase 5, Cyclin-dependent Kinase 5, Ser"
Cyclin-dependent kinase-5(CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in the kidneys, testes, and ovaries. And Its activity has been detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, however, Cdk5 is not activated by cyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits, called p35 and p39. These two activators regulate the spatial and temporal expression of active Cdk5, restricting its activity primarily to post-mitotic neurons. FunctionProbably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000, Optimal dilutions to be determined by the researcher. Positive Control: SH-SY5Y, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-CDK5, Anti-CDKN5, EC=2.7.11.22, Anti-TPKII catalytic subunit, Anti-Cyclin-dependent kinase 5, Anti-Cell division protein kinase 5, Anti-Serine/threonine-protein kinase PSSALRE, Anti-Tau protein kinase II catalytic subunit
Supplier: United States Biological
Supplier-Nr: C2575-10B

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant corresponding to human CDK5, His-tagged, expressed in Baculovirus expressed insect cells.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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