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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
145421.100 | 100 µg | - | - |
3 - 19 business days* |
932.00€
|
CD7 (Cluster of Differentiation Antigen 7, also Leu-9, TP41 and GP40) is a 40-44kD member of the... more
Product information "Anti-CD7 (Cluster of Differentiation Antigen 7, GP40, LEU-9, TP41)"
CD7 (Cluster of Differentiation Antigen 7, also Leu-9, TP41 and GP40) is a 40-44kD member of the Igsuperfamily of proteins. It shows restricted expression, being found on fetal thymocytes, CD34+ myeloid and lymphoid progenitor cells, memory CLA CD45RA+ T cells, and CD56+ IFNgamma secreting NK cells. CD7 binds to both SECTM1/K12 and galectin-1, and when bound to the latter, initiates complex formation with CD43 in cis. Activation of CD7 may result in either cell proliferation or apoptosis, suggesting a contextdependent signaling mechanism. Mature human CD7 is a 215 amino acid (aa) type I transmembrane glycoprotein. It contains a 155aa extracellular region (aa26-180) that shows one Vtype Iglike domain (aa26-130), and a 39 aa C-terminal cytoplasmic domain. There is one potential alternative splice variant that contains a 79aa substitution for aa133240. Over aa26-180, human CD7 shares only 43% aa sequence identity with mouse CD7. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 2.5ug/10e6 cells, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: | United States Biological |
Supplier-Nr: | 145421 |
Properties
Application: | ELISA, FC |
Antibody Type: | Monoclonal |
Clone: | 848438 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Format: | Affinity Purified |
Database Information
UniProt ID : | P09564 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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