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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1959-100 | 100 tests | - |
3 - 11 business days* |
653.00€
|
CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the... more
Product information "Anti-CD59 / Protectin Monoclonal Antibody (Clone:MEM-43)-FITC Conjugated"
CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation. Protein function: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. [The UniProt Consortium]
Keywords: | Anti-CD59, Anti-MIRL, Anti-HRF20, Anti-MACIF, Anti-MIC11, Anti-MAC-IP, Anti-HRF-20, Anti-Protectin, Anti-1F5 antigen, Anti-MEM43 antigen, Anti-CD59 glycoprotein, Anti-MAC-inhibitory protein, Anti-Membrane inhibitor of reactive lysis, Anti-CD59 / Protectin |
Supplier: | Abeomics |
Supplier-Nr: | 30-1959 |
Properties
Application: | FC, IP, IHC |
Antibody Type: | Monoclonal |
Clone: | MEM-43 |
Conjugate: | FITC |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Thymocytes and T lymphocytes |
Database Information
KEGG ID : | K04008 | Matching products |
UniProt ID : | P13987 | Matching products |
Gene ID | GeneID 966 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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