Anti-CD47, clone B6H12.2

Anti-CD47, clone B6H12.2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2069SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody reacts with the Ig domain of... more
Product information "Anti-CD47, clone B6H12.2"
1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody reacts with the Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. Protein function: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. [The UniProt Consortium]
Keywords: Anti-IAP, Anti-MER6, Anti-CD47, Anti-Protein MER6, Anti-Integrin-associated protein, Anti-Leukocyte surface antigen CD47, Anti-Antigenic surface determinant protein OA3, CD47 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2069SAF

Properties

Application: WB, FC, IF, FA (blocking), IHC
Antibody Type: Monoclonal
Clone: B6H12.2
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Intact CD47 purified from placenta was used as the immunogen for this antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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