Anti-CD40

Anti-CD40
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030056.100 100 µl - -

3 - 19 business days*

477.00€
 
CD40 molecule, TNF receptor superfamily member 5. It is a member of the TNF-receptor superfamily.... more
Product information "Anti-CD40"
CD40 molecule, TNF receptor superfamily member 5. It is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Applications: Immunofluorescence: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-CD40, Anti-Bp50, Anti-CDw40, Anti-TNFRSF5, Anti-CD40L receptor, Anti-B-cell surface antigen CD40, Anti-Tumor necrosis factor receptor superfamily member 5
Supplier: United States Biological
Supplier-Nr: 030056

Properties

Application: ELISA
Antibody Type: Monoclonal
Clone: 13B134
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of CD40 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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