Anti-CD38

Anti-CD38
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030052.100 100 µl - -

3 - 19 business days*

477.00€
 
CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages... more
Product information "Anti-CD38"
CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lym- phocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabo- lites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance. Applications: Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-T10, Anti-CD38, EC=3.2.2.5, Anti-cADPr hydrolase 1, Anti-ADP-ribosyl cyclase 1, Anti-Cyclic ADP-ribose hydrolase 1
Supplier: United States Biological
Supplier-Nr: 030052

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 13B130
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of human CD38 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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