Anti-CD30 / Ki-1 Monoclonal Antibody (Clone:MEM-268)

Anti-CD30 / Ki-1 Monoclonal Antibody (Clone:MEM-268)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-30-1315-0.1 100 µg -

3 - 11 business days*

594.00€
 
CD30 is a type I transmembrane glycoprotein of the TNF receptor superfamily. CD30 was originally... more
Product information "Anti-CD30 / Ki-1 Monoclonal Antibody (Clone:MEM-268)"
CD30 is a type I transmembrane glycoprotein of the TNF receptor superfamily. CD30 was originally identified as a cell surface antigen of Hodgkins and Reed-Sternberg cells using monoclonal antibody Ki-1. The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that co-express CD45RO and the IL4 receptor. Soluble form of CD30 (sCD30) serves as a marker reflecting Th2 immune response. Protein function: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B. [The UniProt Consortium]
Keywords: Anti-CD30, Anti-Ki-1 antigen, Anti-CD30L receptor, Anti-Lymphocyte activation antigen CD30, Anti-Tumor necrosis factor receptor superfamily member 8, Anti-CD30 / Ki-1 Monoclonal Antibody (Clone:MEM-268)
Supplier: Abeomics
Supplier-Nr: 30-1315

Properties

Application: FC, IHC
Antibody Type: Monoclonal
Clone: MEM-268
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Expression vector containing CD30 cDNA (booster suspension of THP-1 cell line)
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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