Anti-CD154 / CD40L

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG66057.50 50 µg - -

6 - 14 business days*

520.00€
 
Protein function: Cytokine that binds to CD40/TNFRSF5 (PubMed:1280226). Costimulates T-cell... more
Product information "Anti-CD154 / CD40L"
Protein function: Cytokine that binds to CD40/TNFRSF5 (PubMed:1280226). Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (PubMed:8617933). Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T- cells. Induces tyrosine phosphorylation of isoform 3 of CD28 (PubMed:15067037). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. [The UniProt Consortium]
Keywords: Anti-CD40L, Anti-CD40LG
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG66057

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: human
Immunogen: E. coli derived recombinant Human CD154 / CD40L.(MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LWLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL)
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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