Anti-CD11c, clone ITGAX/1284

Anti-CD11c, clone ITGAX/1284
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3219SAF-100UG 100 µg - -

3 - 10 business days

1 mg/ml in 1X PBS, BSA free, sodium azide free. Recognizes a protein of 145kDa, identified as... more
Product information "Anti-CD11c, clone ITGAX/1284"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues. Protein function: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. [The UniProt Consortium]
Keywords: Anti-CD11C, Anti-ITGAX, Anti-CD11c, Anti-Leu M5, Anti-Integrin alpha-X, Anti-CD11 antigen-like family member C, Anti-Leukocyte adhesion receptor p150,95, Anti-Leukocyte adhesion glycoprotein p150,95 alpha chain, CD11c Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3219SAF-100UG


Application: FC, IF, IHC (paraffin)
Antibody Type: Monoclonal
Clone: ITGAX/1284
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: A partial recombinant protein corresponding to amino acids 637-827 from human ITGAX/CD11c was used as the immunogen for the CD11c antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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