Anti-CD11a (human), PE Conjugated Clone B-B15

Anti-CD11a (human), PE Conjugated Clone B-B15
Item number Size Datasheet Manual SDS Delivery time Quantity Price
DC-852.512.010 100 tests (1 ml) -

3 - 8 business days*

206.00€
 
Specificity: Recognises the aL integrin of LFA-1 complex, a 180 kDa protein, Format:... more
Product information "Anti-CD11a (human), PE Conjugated Clone B-B15"
Specificity: Recognises the aL integrin of LFA-1 complex, a 180 kDa protein, Format: Phosphate-buffered saline with 1% BSA and 0.1% sodium azide, Working Dilution: Reconstitutes with 1 ml deionised water. Use 10µl to label 106 cells or 100 µl of whole blood, Storage: Stable at +2-8°C for six months after reconstitution. DO NOT FREEZE. Protein function: Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R (PubMed:11812992, PubMed:15528364). Integin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15, the interaction is mediated by ITGAL (PubMed:29100055). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Required for generation of common lymphoid progenitor cells in bone marrow, indicating a role in lymphopoiesis. Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). [The UniProt Consortium]
Keywords: Anti-CD11A, Anti-CD11a, Anti-ITGAL, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A, Anti-Leukocyte adhesion glycoprotein LFA-1 alpha chain, Anti-Leukocyte function-associated molecule 1 alpha chain, Anti-Human CD11a Monoclonal
Supplier: Diaclone
Supplier-Nr: 852.512.010

Properties

Application: FC
Antibody Type: Monoclonal
Clone: B-B15
Conjugate: Phycoerythrin
Host: Mouse
Reactivity: Human
Immunogen: Human PBL

Handling & Safety

Storage: +4°C (do not freeze)
Shipping: +20°C (International: °C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H300, H310, H410, EUH032
P Phrases: P262, P264, P270, P273, P280, P321, P330, P391, P301+P310, P302+P352, P361+P364, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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