Anti-CD10

Anti-CD10
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030032.100 100 µl - -

3 - 19 business days*

477.00€
 
CD10(MME): membrane metallo-endopeptidase. This gene encodes a common acute lymphocytic leukemia... more
Product information "Anti-CD10"
CD10(MME): membrane metallo-endopeptidase. This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. Applications: Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-EPN, Anti-SFE, Anti-MME, Anti-NEP, Anti-CD10, Anti-CALLA, Anti-Neprilysin, EC=3.4.24.11, Anti-Enkephalinase, Anti-Atriopeptidase, Anti-Neutral endopeptidase, Anti-Skin fibroblast elastase, Anti-Neutral endopeptidase 24.11
Supplier: United States Biological
Supplier-Nr: 030032

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 13B110
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of CD10 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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