Anti-CCR6 (CD196, Chemokine Receptor 6, CC-CCR-6, C-C chemokine receptor type 6, LARC receptor, GPR-

Anti-CCR6 (CD196, Chemokine Receptor 6, CC-CCR-6, C-C chemokine receptor type 6, LARC receptor, GPR-
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2099-70D.100 100 µg - -

3 - 19 business days*

644.00€
 
CCR6 (C-C chemokine receptor type 6) is a transmembrane glycoprotein and member of the G-protein... more
Product information "Anti-CCR6 (CD196, Chemokine Receptor 6, CC-CCR-6, C-C chemokine receptor type 6, LARC receptor, GPR-"
CCR6 (C-C chemokine receptor type 6) is a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a specific receptor for the C-C chemokine LARC (Liver and activation-regulated chemokine)/MIP-3alpha, a selective chemoattractant which induces calcium flux in CCR6-expressing lymphocytes. CCR6 is preferentially expressed by B cells, memory T cells and immature dendritic cells and plays an important role in B lineage maturation and antigen-driven B cell differentiation. CCR6 acts as a co-receptor for HIV1 infection, and is selectively expressed by mucosa-associated non-Hodgkin's lymphoma, making the interaction between CCR6 and LARC a potential therapeutic target in these malignancies. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:75,000, Western Blot: 1:500, Immunohistochemistry (resin): 1:250, Optimal dilutions to be determined by the researcher. Positive Control: Spleen, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-CKR-L3, Anti-GPRCY4, Anti-CC-CKR-6, Anti-C-C CKR-6
Supplier: United States Biological
Supplier-Nr: C2099-70D

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Reactivity: Human, Mouse
Immunogen: Synthetic peptide YFVSVNTSYYSVDSEMLLCSLQEVRQFSR corresponding to aa8-46 of human CCR6.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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