Anti-CCND3

Anti-CCND3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030028.100 100 µl - -

3 - 19 business days*

479.00€
 
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are... more
Product information "Anti-CCND3"
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:10,000, Western Blot: 1:500-1:2000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-CCND3, Anti-G1/S-specific cyclin-D3
Supplier: United States Biological
Supplier-Nr: 030028

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B106
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse
Immunogen: Purified recombinant fragment of human CCND3 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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