Anti-CCND1

Anti-CCND1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030027.100 100 µl - -

3 - 19 business days*

477.00€
 
During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators... more
Product information "Anti-CCND1"
During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators of the cell cycle the cyclins control important transitions by acting as regulatory subunits of the Cdks. Early in the G1 phase of the cell cycle, cyclin D1 induction is followed by cyclin E induction. This sequential progression is marked early on in G1 by the activation of Cdk4 and in mid to late G1 by the activation of Cdk2 and the hyperphosphorylation of pRB. The final transition into S phase is thought to be dependent on the increased expression and association of cyclin E and Cdk2. In a recent study, Cyclin D1 regulates cellular metabolism, fat cell differentiation and cellular migration. Cyclin D1 is also involved in development and cancer. Cyclin D1 has also been linked to the development and progression of several cancers including breast, bladder, esophagus, and lung. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-BCL1, Anti-BCL-1, Anti-CCND1, Anti-BCL-1 oncogene, Anti-PRAD1 oncogene, Anti-G1/S-specific cyclin-D1, Anti-B-cell lymphoma 1 protein
Supplier: United States Biological
Supplier-Nr: 030027

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B105
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of human CCND1 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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