Anti-CBL-C, NT (Signal Transduction Protein CBL-C, SH3-binding Protein CBL-C, SH3-binding Protein CB

Anti-CBL-C, NT (Signal Transduction Protein CBL-C, SH3-binding Protein CBL-C, SH3-binding Protein CB
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C0013-34-PE.200 200 µl - -

1 - 19 business days

696.00€
 
Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling... more
Product information "Anti-CBL-C, NT (Signal Transduction Protein CBL-C, SH3-binding Protein CBL-C, SH3-binding Protein CB"
Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Applications: Suitable for use in FLISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-1:500, Immunohistochemistry: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-CBL3, Anti-CBLC, EC=6.3.2.-, Anti-RING finger protein 57, Anti-SH3-binding protein CBL-C, Anti-SH3-binding protein CBL-3, Anti-Signal transduction protein CBL-C, Anti-E3 ubiquitin-protein ligase CBL-C
Supplier: United States Biological
Supplier-Nr: C0013-34-PE

Properties

Application: FLISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: Phycoerythrin
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide selected from the N-terminal region of human Cbl-c (KLH).
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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