Anti-Cathepsin D, clone 6j3

Anti-Cathepsin D, clone 6j3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2097-24B.50 50 µl - -

3 - 19 business days*

C2097-24B.100 100 µl - -

3 - 19 business days*

The aspartic protease cathepsin D is one of the major proteolytic enzymes in lysosomes. The... more
Product information "Anti-Cathepsin D, clone 6j3"
The aspartic protease cathepsin D is one of the major proteolytic enzymes in lysosomes. The cathepsin D gene locates on chromosome 11p15.5 and spans approximately 11 kb with nine exons. Initially synthesized as an inactive precursor of pro-cathepsin D, the enzyme is subsequently converted to its active forms by proteolytic processing. Breast cancer cells, unlike normal cells, secrete high levels of pro-cathepsin D. Cathepsin D has been reported to be involved in malignant tumor progression and with prognosis of various human cancers. Applications: Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:250-1:1000, Immunohistochemistry: 1:50-1:100., Optimal dilutions to be determined by the researcher. Recommended Positive Control Tissue: Melanoma, invasive ductal carcinoma, Hybridoma: Derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human cathepsin D protein. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-CTSD, Anti-CPSD, EC=
Supplier: United States Biological
Supplier-Nr: C2097-24B


Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 6j3
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant human Cathepsin D (21-412 aa) purified from E. coli
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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