Anti-Caspase-7

Anti-Caspase-7
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32146 100 µg - -

3 - 10 business days

503.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase-7, Apoptosis-related cysteine... more
Product information "Anti-Caspase-7"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase-7, Apoptosis-related cysteine peptidase, is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. It is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of CASP7 regulates microglia activation through a protein kinase C-delta (PRKCD)-dependent pathway. Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death. [The UniProt Consortium]
Keywords: Anti-MCH3, Anti-CASP7, EC=3.4.22.60, Caspase-7 Antibody
Supplier-Nr: R32146

Properties

Application: WB, IHC (paraffin)
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Rat
Immunogen: Amino acids 117-198 of human Caspase-7 were used as the immunogen for the Caspase-7 antibody. This sequence is from the large subunit.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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