Anti-CASC3 (IHC)

Anti-CASC3 (IHC)
Promotion:

Bethyl is giving away a free permanent marker for every Bethyl purchase until supplies last!

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00690-T 10 µl (5+ slides) -

3 - 9 business days

125.00€
IHC-00690 100 µl (50+ slides) -

3 - 9 business days

456.00€
 
Protein function: Core component of the splicing-dependent multiprotein exon junction complex... more
Product information "Anti-CASC3 (IHC)"
Protein function: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). Stimulates the ATPase and RNA- helicase activities of EIF4A3. Plays a role in the stress response by participating in cytoplasmic stress granules assembly and by favoring cell recovery following stress. Component of the dendritic ribonucleoprotein particles (RNPs) in hippocampal neurons. May play a role in mRNA transport. Binds spliced mRNA in sequence-independent manner, 20-24 nucleotides upstream of mRNA exon-exon junctions. Binds poly(G) and poly(U) RNA homopolymer. [The UniProt Consortium]
Keywords: Anti-Btz, Anti-CASC3, Anti-MLN51, Anti-MLN 51, Anti-Protein CASC3, Anti-Protein barentsz, Anti-Metastatic lymph node gene 51 protein, Anti-Cancer susceptibility candidate gene 3 protein
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00690-T

Properties

Application: IHC, IHC-IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Bovine, Dog, Horse, Rabbit, Swine, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Tasmanian Devil, White-tufted-ear Marmoset, Crab-eating Macaque, African Elephant, Gray Short-tailed Opossum, Northern White-cheeked Gibbon)
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
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