Anti-Carboxypeptidase A1áAntibody / CPA1, clone CPA1/2712

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3986IHC-7ML 7 ml - -

3 - 10 business days*

752.00€
 
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*.... more
Product information "Anti-Carboxypeptidase A1áAntibody / CPA1, clone CPA1/2712"
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*. Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are designated carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events. Protein function: Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. [The UniProt Consortium]
Keywords: Anti-CPA, Anti-CPA1, EC=3.4.17.1, Anti-Carboxypeptidase A1, Carboxypeptidase A1áAntibody / CPA1
Supplier: NSJ Bioreagents
Supplier-Nr: V3986IHC

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: CPA1/2712
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Full length recombinant human protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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