Anti-CAPH2, NT (Condensin-2 Complex Subunit H2, Non-SMC Condensin II Complex, Subunit H2, Chromosome

Anti-CAPH2, NT (Condensin-2 Complex Subunit H2, Non-SMC Condensin II Complex, Subunit H2, Chromosome
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C1077-04-PE.200 200 µl - -

4 - 22 business days

696.00€
 
Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into... more
Product information "Anti-CAPH2, NT (Condensin-2 Complex Subunit H2, Non-SMC Condensin II Complex, Subunit H2, Chromosome"
Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-CAPH2, Anti-NCAPH2, Anti-hCAP-H2, Anti-Kleisin-beta, Anti-Condensin-2 complex subunit H2, Anti-Chromosome-associated protein H2, Anti-Non-SMC condensin II complex subunit H2
Supplier: United States Biological
Supplier-Nr: C1077-04-PE

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide selected from the N-terminal region of human CAPH2 (KLH).
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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