Anti-Calponin-1 (Smooth Muscle Marker) (clone: rCNN1/832) (recombinant monoclonal)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-12-1001-20 20 µg -

3 - 11 business days*

373.00€
 
Multiple isoelectric variants of calponin have been identified, however only two molecular weight... more
Product information "Anti-Calponin-1 (Smooth Muscle Marker) (clone: rCNN1/832) (recombinant monoclonal)"
Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle. Protein function: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. [The UniProt Consortium]
Keywords: Anti-CNN1, Anti-Calponin-1, Anti-Basic calponin, Anti-Calponin H1, smooth muscle, Recombinant Mouse Monoclonal Antibody to Calponin-1 (Smooth Muscle Marker)(Clone : rCNN1/832)
Supplier: Abeomics
Supplier-Nr: 12-1001-20

Properties

Application: FC, IF, IHC
Antibody Type: Monoclonal
Clone: rCNN1/832
Conjugate: No
Host: Mouse
Species reactivity: human, rat
Immunogen: Recombinant full-length human CNN1 protein
Format: Purified

Database Information

UniProt ID : P51911 | Matching products
Gene ID GeneID 1264 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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