Anti-Calponin-1, Rabbit Monoclonal (RM262)

Anti-Calponin-1, Rabbit Monoclonal (RM262)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
REV-31-1143-00-R100 100 µl - -

3 - 9 business days*

483.00€
 
Recombinant Antibody. This antibody reacts to human or mouse Calponin-1. Applications: WB, ICC.... more
Product information "Anti-Calponin-1, Rabbit Monoclonal (RM262)"
Recombinant Antibody. This antibody reacts to human or mouse Calponin-1. Applications: WB, ICC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Calponin-1 is a 34 kDa thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It interacts with actin, tropomyosin and calmodulin. Calponin-1 binds actin to promote and sustain polymerization. The binding of calponin to F-actin inhibits the MgATPase activity of smooth muscle myosin. The expression of Calponion-1 is specific to differentiated mature smooth muscle cells, suggesting a role in contractile functions. It is up-regulated in smooth muscle tissues during postnatal development with a higher content in phasic smooth muscle of the digestive tract. Calponin-1 has been found to be useful in differentiating benign sclerosing lesions of the breast from carcinoma. Calponin-1 positivity has also been noted in malignant myoepithelioma and pleomorphic adenoma of salivary gland origin, as well as angiomatoid malignant fibrous histiocytoma.
Keywords: Calponin H1, Smooth Muscle
Supplier: RevMAb Biosciences
Supplier-Nr: 31-1143-00

Properties

Application: WB, ICC
Antibody Type: Monoclonal
Clone: RM262
Conjugate: No
Host: Rabbit
Species reactivity: human
Format: Purified

Database Information

UniProt ID : P51911 | Matching products
Gene ID GeneID 1264 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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