Anti-Calpain 6 (CAPN6, Calpain-like protease X-linked, Calpamodulin, CalpM, CALPM, CANPX, CAPNX, DJ9

Anti-Calpain 6 (CAPN6, Calpain-like protease X-linked, Calpamodulin, CalpM, CALPM, CANPX, CAPNX, DJ9
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C1035-28M.100 100 µg - -

3 - 19 business days*

511.00€
 
Calpains make up a ubiquitously expressed, well-conserved family of calcium-dependent cysteine... more
Product information "Anti-Calpain 6 (CAPN6, Calpain-like protease X-linked, Calpamodulin, CalpM, CALPM, CANPX, CAPNX, DJ9"
Calpains make up a ubiquitously expressed, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. This large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes as their activation can be triggered by calcium influx and oxidative stress. Calpain 6 (CAPN6) is most similar to Calpain 5, the C-terminal region of CAPN6 lacks homology to the calmodulin-like domain of other vertebrate calpains. CAPN6 is thought to be involved in the regulation of microtubule dynamics and cytoskeletal organization. CAPN6 has also been recently identified as an HIV dependency factor (HDF), suggesting that CAPN6 may be an important drug target in HIV treatment. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml , Optimal dilutions to be determined by the researcher. Positive Control: Rat Lung Tissue Lysate, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-Calpain-6
Supplier: United States Biological
Supplier-Nr: C1035-28M

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide corresponding to 18aa from near the carboxy terminus of human CAPN6.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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