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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C1035-03L.100 | 100 µg | - | - |
3 - 19 business days* |
675.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CaM kinase I belongs to a calcium-triggered signalling cascade involved in trasncriptional... more
Product information "Anti-Calmodulin-dependent Protein Kinase Type 1 (CaM-KI, CaM kinase I alpha, CAMKI-alpha)"
CaM kinase I belongs to a calcium-triggered signalling cascade involved in trasncriptional regulation, hormone production, translational regulation, regulation of actin filament organisation and neurite outgrowth. CaM kinase I is involved in calcium-dependent activation of the ERK pathway. It phosphorylates proteins with the substrate consensus sequence [MVLIF}-x-R-x(2)-[ST]-x(3)-[MVLIF]. It is activated by calcium ions or calmodulin. It reaches its maximum catalytic activity when phosphorylated by CAMKK1 or CAMKK2. CaM kinase I has a length of 370 amino acids (unprocessed precursor) and a predicted molecular weight of 41.3KDa. It is a monomer that exists in many tissues and is located within the cytoplasm or nucleus. It belongs to the protein kinase superfamily, the CAMK Ser/Thr protein kinase family and the CaMK subfamily. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilution: Western Blot: Denaturing conditions in HL-60 lysates, ELISA (Sandwich): Detection limit 0.3ng/ml with recombinant GST tagged CaM Kinase 1, Optimal dilution determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-CAMK1, EC=2.7.11.17, Anti-CaMKI-alpha, Anti-Calcium/calmodulin-dependent protein kinase type 1 |
Supplier: | United States Biological |
Supplier-Nr: | C1035-03L |
Properties
Application: | ELISA, WB |
Antibody Type: | Monoclonal |
Clone: | 9G328 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Partial recombinant protein of human CaM kinase 1 (aa 271-370) with a GST tag. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K08794 | Matching products |
UniProt ID : | Q14012 | Matching products |
Gene ID | GeneID 8536 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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