Anti-C1R

C1R (Complement C1r) is a Protein Coding gene. Diseases associated with C1R includeEhlers-Danlos Syndrome, Periodontal Type, 1andPeriodontal Ehlers-Danlos Syndrome. Among its related pathways areCreation of C4 and C2 activatorsandComplement and coagulation cascades. Gene Ontology (GO) annotations related to this gene includecalcium ion bindingandserine-type peptidase activity. An important paralog of this gene isMASP2. Protein function: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. [The UniProt Consortium]