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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-36-1482-100 | 100 µg | - |
3 - 11 business days* |
853.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
It recognizes a transcription factor of 64-67kDa, identified as c-myc. This MAb shows no... more
Product information "Anti-c-Myc Oncoprotein(MYC275 + MYC909)"
It recognizes a transcription factor of 64-67kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCL s) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final diagnosis of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differential diagnoses of the lymphomas. Protein function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000). [The UniProt Consortium]
Keywords: | Anti-MYC, Anti-BHLHE39, Anti-bHLHe39, Anti-Proto-oncogene c-Myc, Anti-Transcription factor p64, Anti-Myc proto-oncogene protein, Anti-Class E basic helix-loop-helix protein 39, Monoclonal Antibody to c-Myc Oncoprotein(MYC275 + MYC909) |
Supplier: | Abeomics |
Supplier-Nr: | 36-1482 |
Properties
Application: | FC, IF, IHC |
Antibody Type: | Monoclonal |
Clone: | MYC275 + MYC909 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, |
Immunogen: | Recombinant human c-myc protein |
Format: | Affinity Purified |
Database Information
KEGG ID : | K04377 | Matching products |
UniProt ID : | P01106 | Matching products |
Gene ID | GeneID 4609 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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