Anti-c-Myc Oncoprotein(Clone: MYC909)

Anti-c-Myc Oncoprotein(Clone: MYC909)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-36-1481 100 µg -

2 - 11 business days

500.00€
ABE-36-1481-100 100 µg -

2 - 11 business days

500.00€
 
It recognizes a transcription factor of 64-67kDa, identified as c-myc. This MAb shows no... more
Product information "Anti-c-Myc Oncoprotein(Clone: MYC909)"
It recognizes a transcription factor of 64-67kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCL's) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final diagnosis of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differential diagnoses of the lymphomas. Protein function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000). [The UniProt Consortium]
Keywords: Anti-MYC, Anti-BHLHE39, Anti-bHLHe39, Anti-Proto-oncogene c-Myc, Anti-Transcription factor p64, Anti-Myc proto-oncogene protein, Anti-Class E basic helix-loop-helix protein 39, Monoclonal Antibody to c-Myc Oncoprotein(Clone: MYC909)
Supplier: Abeomics
Supplier-Nr: 36-1481

Properties

Application: FC, IF, IHC
Antibody Type: Monoclonal
Clone: MYC909
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant human c-myc protein
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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