Anti-c-Fos, clone RM374

Anti-c-Fos, clone RM374
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG40717.50 50 µl - -

6 - 14 business days*

439.00€
 
Protein function: Nuclear phosphoprotein which forms a tight but non- covalently linked complex... more
Product information "Anti-c-Fos, clone RM374"
Protein function: Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD- binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum. [The UniProt Consortium]
Keywords: Anti-FOS, Anti-G0S7, Anti-Proto-oncogene c-Fos, Anti-Cellular oncogene fos, Anti-G0/G1 switch regulatory protein 7
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG40717

Properties

Application: IHC (paraffin), WB
Antibody Type: Monoclonal
Clone: RM374
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Mouse, Rat)
Immunogen: Synthetic peptide around the N-terminus of Human c-Fos
MW: 41 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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