Anti-BTK, ID (Tyrosine-protein Kinase BTK, Bruton Tyrosine Kinase, Agammaglobulinaemia Tyrosine Kina

Anti-BTK, ID (Tyrosine-protein Kinase BTK, Bruton Tyrosine Kinase, Agammaglobulinaemia Tyrosine Kina
Item number Size Datasheet Manual SDS Delivery time Quantity Price
B5000-01F-PE.200 200 µl - -

3 - 19 business days*

993.00€
 
BTK plays a crucial role in B-cell ontogeny. This protein transiently phosphorylates GTF2I on... more
Product information "Anti-BTK, ID (Tyrosine-protein Kinase BTK, Bruton Tyrosine Kinase, Agammaglobulinaemia Tyrosine Kina"
BTK plays a crucial role in B-cell ontogeny. This protein transiently phosphorylates GTF2I on tyrosine residues in response to B-cell receptor cross-linking. Defects in BTK are the cause of X-linked agammaglobulinemia type 1 (XLA). XLA is a humoral immunodeficiency disease which results in developmental defects in the maturation pathway of B-cells. Affected boys have normal levels of pre-B-cells in their bone marrow but virtually no circulating mature B-lymphocytes. This results in a lack of immunoglobulins of all classes and leads to recurrent bacterial infections like otitis, conjunctivitis, dermatitis, sinusitis or fatal sepsis or meningitis within the first years of life. Applications: Suitable for use in FLISA, Western Blot, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-BPK, Anti-ATK, Anti-BTK, Anti-AGMX1, EC=2.7.10.2, Anti-Bruton tyrosine kinase, Anti-B-cell progenitor kinase, Anti-Tyrosine-protein kinase BTK, Anti-Agammaglobulinemia tyrosine kinase
Supplier: United States Biological
Supplier-Nr: B5000-01F-PE

Properties

Application: FLISA, IF, IHC, WB
Antibody Type: Polyclonal
Conjugate: Phycoerythrin
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic peptide selected from the center region of human BTK (KLH).
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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