Anti-beta-HCG (Clone: PC-2)

beta-HCG(beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain(CGB). It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, beta-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. beta-HCG is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor. Protein function: Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role for pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. [The UniProt Consortium]