Anti-BCL-XL (Ab-62)

Anti-BCL-XL (Ab-62)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-35-1415-50 50 µl -

3 - 11 business days*

574.00€
 
Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by... more
Product information "Anti-BCL-XL (Ab-62)"
Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis. Protein function: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. [The UniProt Consortium]
Keywords: Anti-BAD, Anti-BBC6, Anti-Bcl2-L-8, Anti-Bcl-2-like protein 8, Anti-Bcl-2-binding component 6, Anti-Bcl2 antagonist of cell death, Anti-Bcl2-associated agonist of cell death, Anti-Bcl-xL/Bcl-2-associated death promoter, Polyclonal Antibody to BCL-XL (Ab-6
Supplier: Abeomics
Supplier-Nr: 35-1415-50

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Peptide sequence around aa.60~64 (A-D-S-P-A) derived from human BCL-XL .
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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