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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V9071SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in sterile PBS, BSA free, sodium azide free. Recognizes a protein of 21kDa, identified as... more
Product information "Anti-Bax, clone SPM336"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Recognizes a protein of 21kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2. Protein function: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. [The UniProt Consortium]
Keywords: | Anti-BAX, Anti-BCL2L4, Anti-Bcl2-L-4, Anti-Bcl-2-like protein 4, Anti-Apoptosis regulator BAX, Anti-Bax Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V9071SAF |
Properties
Application: | FC, IF, WB, IHC |
Antibody Type: | Monoclonal |
Clone: | SPM336 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, monkey |
Immunogen: | Amino acids 3-16 (GSGEQPRGGGPTSS) from the human protein were used as the immunogen for this anti-Bax antibody. |
Format: | Purified |
Database Information
KEGG ID : | K02159 | Matching products |
UniProt ID : | Q07812 | Matching products |
Gene ID | GeneID 581 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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