Anti-BAX (BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4)

Anti-BAX (BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030801.100 100 µl - -

3 - 19 business days*

728.00€
 
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form... more
Product information "Anti-BAX (BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4)"
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:500~8000, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: 030801

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 557CT5.2.1
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Purified His-tagged BAX protein (fragment).
Purity: Ascites
Format: Ascites

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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