Anti-Basic Cytokeratin (HMW / Type II), clone SPM116

Anti-Basic Cytokeratin (HMW / Type II), clone SPM116
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7399IHC-7ML 7 ml - -

3 - 10 business days*

752.00€
 
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*.... more
Product information "Anti-Basic Cytokeratin (HMW / Type II), clone SPM116"
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*. This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1), 64kDa (CK3), 59kDa (CK4), 58kDa (CK5), 56kDa (CK6), 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50, 48, 46, 45, and 40kDa. This MAb recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. Protein function: Probably contributes to terminal cornification. [The UniProt Consortium]
Keywords: Anti-K2P, Anti-K76, Anti-KRT2B, Anti-KRT76, Anti-CK-2P, Anti-Keratin-76, Anti-Cytokeratin-2P, Anti-Type-II keratin Kb9, Anti-Keratin, type II cytoskeletal 2 oral, Basic Cytokeratin Antibody (HMW / Type II)
Supplier: NSJ Bioreagents
Supplier-Nr: V7399IHC

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: SPM116
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Solubilized cytokeratin extract from human stratum corneum was used as the immunogen.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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