Anti-BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS Receptor 3

Anti-BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS Receptor 3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
B0003-68B.100 100 µg - -

3 - 19 business days*

462.00€
 
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in... more
Product information "Anti-BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS Receptor 3"
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF- R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kappaB and c-Jun N-terminal kinase. Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilutions: Western Blot: 0.5-4 ug/ml, Optimal dilutions to be determined by the researcher. Control Peptide: B0003-68B1 , Storage and Stability:, May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: B0003-68B

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide surrounding aa159of mouse BAFF-R.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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