Anti-ATM

Anti-ATM
Item number Size Datasheet Manual SDS Delivery time Quantity Price
029974.100 100 µl - -

3 - 19 business days*

505.00€
 
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an... more
Product information "Anti-ATM"
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.Tissue specificity: Found in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon and leukocytes. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-ATM, EC=2.7.11.1, Anti-A-T mutated, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated
Supplier: United States Biological
Supplier-Nr: 029974

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B52
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of human ATM expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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