Anti-ASC1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG40258.100 100 µl - -

6 - 14 business days

483.00€
 
Protein function: Transcription coactivator which associates with nuclear receptors,... more
Product information "Anti-ASC1"
Protein function: Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation (PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF- kappa-B (PubMed:12077347). May play a role in the development of neuromuscular junction (PubMed:26924529). May play a role in late myogenic differentiation. [The UniProt Consortium]
Keywords: Anti-ASC-1, Anti-TRIP-4, Anti-TR-interacting protein 4, Anti-Activating signal cointegrator 1, Anti-Thyroid receptor-interacting protein 4
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG40258100

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein corresponding to aa. 282-581 of Human ASC1 (NP_057297.2)
MW: 66 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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