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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A3570-66R.100 | 100 µg | - | - |
3 - 19 business days* |
962.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ARHGAP1(also p50-RhoGAP and CDC42 GTPase-activating protein) is a 50kD member of the ARHGAP... more
Product information "Anti-ARHGAP1 (Rho GTPase-activating Protein 1, Rho-type GTPase-activating Protein 1, MacGAP)"
ARHGAP1(also p50-RhoGAP and CDC42 GTPase-activating protein) is a 50kD member of the ARHGAP family of proteins. It is preferentially expressed in epithelium, and serves as a cytoplasmic protein that deactivates Rho-family GTPases. It does so by contributing an Arg residue (Arg282)to Cdc42 and RhoA, which activates their intrinsic GTPase activity and converts GTP-associated molecules into inactivating GDP molecules. Human ARHGAP1 is 439aa in length and contains one CRAL-TRIO domain that binds small lipophilic molecules (aa53-218), an SH3 binding site (aa228-238) and one C-terminal RhoGAP domain (aa244-431). There are phosphorylation sites at Ser51 and Tyr65. There is one potential splice form with a 24aa substitution for (aa1-150)coupled to a 26aa substitution for (aa300-439), Over (aa1-62, human ARHGAP1 shares 96% aa identity with mouse ARHGAP1. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.2ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-CDC42GAP, Anti-p50-RhoGAP, Anti-Rho GTPase-activating protein 1, Anti-CDC42 GTPase-activating protein, Anti-GTPase-activating protein rhoOGAP, Anti-Rho-type GTPase-activating protein 1, Anti-Rho-related small GTPase protein activator |
Supplier: | United States Biological |
Supplier-Nr: | A3570-66R |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Sheep |
Species reactivity: | human |
Immunogen: | Recombinant corresponding to aa1-62 from human ARHGAP1 expressed in E. coli (Q07960). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K18470 | Matching products |
UniProt ID : | Q07960 | Matching products |
Gene ID | GeneID 392 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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