Anti-AQP4, clone CL0178

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-AMAb90537.25 25 µl -

7 - 10 business days*

300.00€
ATA-AMAb90537.100 100 µl -

7 - 10 business days*

421.00€
 
Protein function: Forms a water-specific channel (PubMed:7559426, PubMed:8601457,... more
Product information "Anti-AQP4, clone CL0178"
Protein function: Forms a water-specific channel (PubMed:7559426, PubMed:8601457, PubMed:19383790). Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP. Plays a redundant role in urinary water homeostasis and urinary concentrating ability. [The UniProt Consortium] Validated by orthogonal and standard strategies. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 93% and to rat: 92%. Epitope specificity: FKRRFKEAFS.
Keywords: Anti-WCH4, Anti-AQP4, Anti-MIWC, Anti-AQP-4, Anti-Aquaporin-4, Anti-Mercurial-insensitive water channel
Supplier: Atlas Antibodies
Supplier-Nr: AMAb90537

Properties

Application: WB, IHC
Antibody Type: Monoclonal
Clone: CL0178
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: CPDVEFKRRF KEAFSKAAQQ TKGSYMEVED NRSQVETDDL ILKPGVVHVI DVDRGEEKKG KDQSGEVLSS V (ATA-APrEST73067)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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