Anti-Apolipoprotein E2 (Apo E2, APOE 2, APOE-2, APOE2, Apolipoprotein E, AD2)

Anti-Apolipoprotein E2 (Apo E2, APOE 2, APOE-2, APOE2, Apolipoprotein E, AD2)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2299-76U.100 100 µg - -

3 - 19 business days*

473.00€
 
ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important... more
Product information "Anti-Apolipoprotein E2 (Apo E2, APOE 2, APOE-2, APOE2, Apolipoprotein E, AD2)"
ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. Defects in ApoE are a cause of hyperlipoproteinemia type III. ApoE exists in three major isoforms, E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. E2 allele carriers had significantly lower levels of total cholesterol, low-density lipoprotein cholesterol, and non-high-density lipoprotein cholesterol, as well as increased ApoE levels. ApoE2 is a 34.3kD protein containing 300 amino acid residues. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.5-4ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: A2299-76K Apolipoprotein E2, Recombinant, Human, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: A2299-76U

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: E. coli expressed recombinant human ApoE2.
MW: 34,3 kD
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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