Anti-Apolipoprotein E (ApoE, AD2, MGC1571, Apoprotein, Apolipoprotein E, Apolipoprotein E3, Alzheime

Anti-Apolipoprotein E (ApoE, AD2, MGC1571, Apoprotein, Apolipoprotein E, Apolipoprotein E3, Alzheime
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2299-75D.100 100 µg - -

3 - 19 business days*

725.00€
 
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from... more
Product information "Anti-Apolipoprotein E (ApoE, AD2, MGC1571, Apoprotein, Apolipoprotein E, Apolipoprotein E3, Alzheime"
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32000, Western Blot: 0.1-0.3ug/ml , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-Apo-E
Supplier: United States Biological
Supplier-Nr: A2299-75D

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Reactivity: Human
Immunogen: Synthetic peptide of ApoE.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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