Anti-APH1, NT (Gamma-secretase Subunit APH-1A, APH-1a, APH-1a, Aph-1alpha, Presenilin-stabilization

Anti-APH1, NT (Gamma-secretase Subunit APH-1A, APH-1a, APH-1a, Aph-1alpha, Presenilin-stabilization
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2296-84A-FITC.200 200 µl - -

3 - 19 business days*

721.00€
 
APH1 is an essential subunit of the gamma-secretase complex, an endoprotease complex that... more
Product information "Anti-APH1, NT (Gamma-secretase Subunit APH-1A, APH-1a, APH-1a, Aph-1alpha, Presenilin-stabilization"
APH1 is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). The gamma-secretase complex is minimally composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2, although other components may exist. APH1 probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Applications: Suitable for use in FLISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-1:500, Immunohistochemistry: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-PSF, Anti-APH1A, Anti-APH-1a, Anti-CGI-78, Anti-Aph-1alpha, Anti-Gamma-secretase subunit APH-1A, Anti-Presenilin-stabilization factor
Supplier: United States Biological
Supplier-Nr: A2296-84A-FITC

Properties

Application: FLISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: FITC
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide selected from the N-terminal region of human APH1 (KLH).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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