Anti-APH1, NT (Gamma-secretase Subunit APH-1A, APH-1a, APH-1a, Aph-1alpha, Presenilin-stabilization

Anti-APH1, NT (Gamma-secretase Subunit APH-1A, APH-1a, APH-1a, Aph-1alpha, Presenilin-stabilization
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2296-84A-Biotin.200 200 µl - -

3 - 19 business days*

721.00€
 
APH1 is an essential subunit of the gamma-secretase complex, an endoprotease complex that... more
Product information "Anti-APH1, NT (Gamma-secretase Subunit APH-1A, APH-1a, APH-1a, Aph-1alpha, Presenilin-stabilization"
APH1 is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). The gamma-secretase complex is minimally composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2, although other components may exist. APH1 probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-1:500, Immunohistochemistry: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-PSF, Anti-APH1A, Anti-APH-1a, Anti-CGI-78, Anti-Aph-1alpha, Anti-Gamma-secretase subunit APH-1A, Anti-Presenilin-stabilization factor
Supplier: United States Biological
Supplier-Nr: A2296-84A-Biotin

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: Biotin
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide selected from the N-terminal region of human APH1 (KLH).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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