Anti-Apelin

Anti-Apelin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R30574 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Apelin is a neuropeptide expressed in the... more
Product information "Anti-Apelin"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei that acts on specific receptors located on vasopressinergic neurons. The gene is at Xq25-q26.3, based on sequence similarity between the Apelin sequence and a chromosome X PAC clone. This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. Protein function: Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior. [The UniProt Consortium]
Keywords: Anti-APEL, Anti-APLN, Apelin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R30574

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: An amino acid sequence from the C-terminus of Apelin (RKFRRQRPRLSHKGPMPF) was used as the immunogen for this Apelin antibody (100% homologous in human, mouse and rat).
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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