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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
REV-31-1311-00-R100 | 100 µl | - | - |
3 - 9 business days* |
483.00€
|
Recombinant Antibody. This antibody RM424 reacts to human Annexin A1. Application: IHC, WB .... more
Product information "Anti-Annexin A1 (human), Rabbit Monoclonal (RM424)"
Recombinant Antibody. This antibody RM424 reacts to human Annexin A1. Application: IHC, WB . Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. The annexin superfamily consists of 13 calcium or calcium and phospholipid binding proteins with high biological and structural homology. Annexin-1 (ANXA1) is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Loss of function or expression of this gene has been detected in multiple tumors. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity, can accumulate on internalized vesicles after EGF-stimulated endocytosis and may be required for a late stage in inward vesiculation. Annexin A1 has also been identified as one of the 'eat-me' signals on apoptotic cells that are to be recognized and ingested by phagocytes. Annexin A1, as an endogenous anti-inflammatory mediator, has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis and tumorigenesis and cancer development.
Keywords: | Lipocortin-1, p35, Annexin-1, Calpactin-2, Calpactin II, Lipocortin I, Chromobindin-9, Phospholipase A2 Inhibitory Protein |
Supplier: | RevMAb Biosciences |
Supplier-Nr: | 31-1311-00 |
Properties
Application: | IHC, WB |
Antibody Type: | Monoclonal |
Clone: | RM424 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Format: | Purified |
Database Information
KEGG ID : | K17091 | Matching products |
UniProt ID : | P04083 | Matching products |
Gene ID | GeneID 301 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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