Anti-Annexin A1 (human), Rabbit Monoclonal (RM424)

Anti-Annexin A1 (human), Rabbit Monoclonal (RM424)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
REV-31-1311-00-R100 100 µl - -

3 - 9 business days*

483.00€
 
Recombinant Antibody. This antibody RM424 reacts to human Annexin A1. Application: IHC, WB .... more
Product information "Anti-Annexin A1 (human), Rabbit Monoclonal (RM424)"
Recombinant Antibody. This antibody RM424 reacts to human Annexin A1. Application: IHC, WB . Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. The annexin superfamily consists of 13 calcium or calcium and phospholipid binding proteins with high biological and structural homology. Annexin-1 (ANXA1) is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Loss of function or expression of this gene has been detected in multiple tumors. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity, can accumulate on internalized vesicles after EGF-stimulated endocytosis and may be required for a late stage in inward vesiculation. Annexin A1 has also been identified as one of the 'eat-me' signals on apoptotic cells that are to be recognized and ingested by phagocytes. Annexin A1, as an endogenous anti-inflammatory mediator, has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis and tumorigenesis and cancer development.
Keywords: Lipocortin-1, p35, Annexin-1, Calpactin-2, Calpactin II, Lipocortin I, Chromobindin-9, Phospholipase A2 Inhibitory Protein
Supplier: RevMAb Biosciences
Supplier-Nr: 31-1311-00

Properties

Application: IHC, WB
Antibody Type: Monoclonal
Clone: RM424
Conjugate: No
Host: Rabbit
Species reactivity: human
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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